Skip to main content
. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Biomaterials. 2010 Sep 19;32(2):410–418. doi: 10.1016/j.biomaterials.2010.08.105

Figure 2. Micropatterning leads to similar morphology and alignment in primary and passaged VSMCs.

Figure 2

(A) Representative phase contrast images of sub-confluent primary, non-passaged (more contractile) and passaged (more synthetic) VSMCs. (B) Primary VSMC area (solid) was unaffected by patterning while passaged VSMC area (open) decreased with decreasing lane width. (C) Primary and passaged VSMCs became increasingly elongated in shape with decreasing lane width. (D) Primary and passaged VSMCs became increasingly aligned within 5° of the pattern as lane width decreased; non-patterned VSMCs had no preferred orientation. B & C show mean ± 2SEM for n = 50 cells per condition. * indicates significant difference for p < 0.05.