. Author manuscript; available in PMC: 2011 Oct 30.

Published in final edited form as: Adv Drug Deliv Rev. 2010 Aug 17;62(13):1218–1226. doi: 10.1016/j.addr.2010.08.007

Table 1.

Human nuclear receptors and the solved LBD structures

Classic Receptors	Structure	Adopted Orphan receptors	Structure	Orphan Receptors	Structure^a
AR	[65]	CAR	[19; 77; 78]	COUP-TF (I, II, III)^b	[21]
ER (α, β)	[66; 67]	ERR (α, β, γ)	[27; 79]	Dax-1^b	[10]
GR	[44]	FXR	[80; 81]	RORγ^b	[24]
MR	[68; 69; 70]	HNF4 (α, γ)	[54; 55]	GCNF	-
PR	[71]	LXR (α, β)	[82; 83]	NGF1-B (α, β, γ)	[56]
RAR (α, β, γ)	[15; 73; 74]	PPAR (α, γ, δ)	[30; 52; 84]	PNR	-
TR (α, β)	[16; 75]	PXR	[29]	RevErbA^b	[36]
VDR	[76]	ROR (α, β)	[72; 85]	SHP	-
		RXR (α, β, γ)	[14; 86]	TLX	-
		LRH	[87]	TR2, TR4	-
		SF1	[88; 89]

A “-” indicates the structure unsolved.

The structures were published in most recent three years (between 2007 and 2010).