A) Comparison between normothermic control and hypothermia patients’ serum creatinine (CREAT), and B) serum blood urea nitrogen (BUN). Individual patients are shown in grey in the background (solid lines, hypothermia; dashed lines, normothermia controls). Each thick line represents a group (black, hypothermia; hatched, normothermia), with median and interquartile range values shown at each time-point. Bl, baseline; d2, day 2 (post-treatment, at completion of hypothermia and re-warm); d7, day 7.