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. Author manuscript; available in PMC: 2011 Dec 21.
Published in final edited form as: Mutat Res. 2010 Sep 6;703(2):191–199. doi: 10.1016/j.mrgentox.2010.08.020

Figure 6.

Figure 6

Output from the hockey-stick program [19] is shown for two independent ethyl nitrosourea (ENU) experiments. The frequency (%) of micronuclei determined via flow cytometric analysis is graphed as a function of ENU concentration µg/ml). Whereas the solid line indicates the best fit, the dashed line shows the hockey stick based on the lower limit of a confidence interval for the threshold dose. The results and statistically significant p-values suggest that the hockey stick model is a better description of the dose-response relationships than a linear fit.