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. Author manuscript; available in PMC: 2011 Oct 30.
Published in final edited form as: Adv Drug Deliv Rev. 2010 Aug 11;62(13):1299–1306. doi: 10.1016/j.addr.2010.08.003

Figure 3.

Figure 3

Implication of LXR ligands in dopaminergic neuron production. Embryonic stem cells can be induced to differentiate into midbrain neural progenitors by the treatment of Shh and Fgf8. These cells can be further induced into dopaminergic neurons by LXR ligands, oxysterols, which promotes dopaminergic neuron induction and inhibits glial differentiation.