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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Dev Dyn. 2010 Dec;239(12):3182–3191. doi: 10.1002/dvdy.22460

Figure 7.

Figure 7

Coronary embryonic free EC density is enhanced in the presence of EMSCs and is dependent on FGF signaling (A, B, C). EC density is markedly reduced when FGFR1-DN or soluble FGFR1-IIIc are added to the explants containing EMSCs; **, ρ<0.001 (D). The conditioned media from wells containing both heart explants and EMSCs have much higher levels of SDF-1α (E). The SDF-1α level is dependent on the number of EMSCs added. When heart explants are cultured in the absence of EMSCs, the cultured medium contains about 35 ρg/ml of SDF-1α (F). If 10k and 25K EMSCs are cultured alone (no heart explant), the SDF-1α in the conditioned media is nearly 2.7 and 12 times higher, respectively, than that observed in heart explants.