Table 1.

Baseline characteristics by intervention group.

	Estrogen Trial (ET)					Estrogen Plus Progestogen Trial (EPT)
	Active n=453		Placebo n=474		p¹	Active n=543		Placebo n=471		p²
	Mean	SD	Mean	SD	p¹	Mean	SD	Mean	SD	p²
Age (y)	63.3	7.6	63.4	7.6	0.78	63.2	7.2	63.4	7.1	0.76
Time since menopause (y)	21.9	8.1	22.5	8.7	0.43	13.3	8.9	13.8	8.1	0.44
Dietary energy intake (kcal)	1717.3	957.7	1660.9	865.5	0.35	1731.6	823.9	1682.3	808.5	0.34
Dietary protein (g)	70.4	37.0	67.9	36.6	0.31	71.7	34.4	69.9	35.6	0.40
Dietary calcium (mg)	791.4	481.8	767.7	466.5	0.45	839.0	466.0	819.5	505.4	0.53
Dietary vitamin d (mcg)	4.0	2.8	4.2	3.2	0.48	4.3	3.0	4.3	3.1	0.78
Total weekly recreational energy expenditure (MET)	10.1	12.8	9.3	11.4	0.43	11.4	14.6	11.9	14.6	0.65

	N	%	N	%	p¹	N	%	N	%	p²

Physical functioning score ≥ 90					0.31					0.89
no	323	73.6	328	70.5		332	61.9	285	62.4
yes	116	26.4	137	29.5		204	38.1	172	37.6
History of pre-study fracture					0.15					0.89
no	202	57.39%	216	62.79%		232	62.70%	237	63.20%
yes	150	42.61%	128	37.21%		138	37.30%	138	36.80%
Ethnicity					0.26					0.06
White	338	74.8	337	71.1		447	82.5	385	81.7
Black	76	16.8	98	20.7		45	8.3	54	11.5
Hispanic	32	7.1	34	7.2		39	7.2	22	4.7
American Indian/Alaskan
Native	3	0.7	4	0.8		4	0.7	8	1.7
Asian/Pacific Islander	0	0.0	1	0.2		4	0.7	0	0.0
Other	3	0.7	0	0.0		3	0.6	2	0.4
Hormone use					0.11					0.83
Never	268	59.2	295	62.2		429	79.2	369	78.3
Past	162	35.8	144	30.4		95	17.5	83	17.6
Current³	23	5.1	35	7.4		18	3.3	19	4.0
Smoking					0.58					0.87
Never	257	57.1	253	54.1		294	54.5	244	53.3
Past	145	32.2	157	33.5		189	35.1	168	36.7
Current	48	10.7	58	12.4		56	10.4	46	10.0
Alcohol use					0.57					0.56
Non-drinker	199	44.4	223	47.5		210	39.0	176	37.8
<7 drinks per week	224	50.0	218	46.5		282	52.3	240	51.5
>7 drinks per week	25	5.6	28	6.0		47	8.7	50	10.7

comparison between active and placebo for ET trial

comparison between active and placebo for EPT trial

required 3 month washout period

MET, metabolic equivalent