Table 2.
Baseline body composition measurements by intervention group and change in body composition from baseline to year 6 (B-Y6)
| Estrogen Trial (ET) |
Estrogen plus Progestogen Trial (EPT) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Active (n=453) | Placebo (n=474) | p1 | Active (n=543) | Placebo (n=471) | p2 | |||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||
| Baseline Anthropometric measures | ||||||||||
| Weight (kg) | 77.71 | 15.61 | 78.01 | 15.63 | 0.77 | 73.36 | 14.73 | 73.94 | 15.24 | 0.54 |
| BMI (kg/m2) | 30.00 | 5.61 | 29.86 | 5.53 | 0.70 | 28.14 | 5.40 | 28.30 | 5.50 | 0.65 |
| Waist (cm) | 90.11 | 13.80 | 89.92 | 12.45 | 0.82 | 85.45 | 12.22 | 86.32 | 13.11 | 0.28 |
| Baseline Tissue specific measures | ||||||||||
| Fat Mass (kg) | 35.91 | 11.41 | 35.77 | 11.42 | 0.85 | 32.52 | 11.00 | 32.51 | 11.19 | 0.99 |
| Percent Fat Mass (%) | 46.02 | 6.76 | 45.67 | 6.69 | 0.43 | 43.96 | 7.37 | 43.62 | 7.30 | 0.46 |
| Lean Mass (kg) | 38.49 | 5.45 | 38.82 | 5.77 | 0.36 | 37.73 | 5.17 | 38.23 | 5.42 | 0.13 |
| Percent Lean Mass (%) | 51.26 | 6.52 | 51.54 | 6.31 | 0.50 | 53.23 | 7.06 | 53.58 | 7.05 | 0.43 |
| Change in Tissue specific measures from Baseline to Year 6 | ||||||||||
| (n=323) | (n=350) | (n=392) | (n=337) | |||||||
| Fat Mass (kg) | 0.05 | 5.68 | 0.12 | 5.50 | 0.87 | 0.64 | 5.43 | 0.43 | 5.33 | 0.59 |
| Percent Fat Mass (%) | 0.01 | 0.16 | 0.01 | 0.16 | 0.96 | 0.03 | 0.23 | 0.02 | 0.18 | 0.47 |
| Lean Mass (kg) | −0.44 | 2.28 | −0.50 | 2.45 | 0.72 | −0.29 | 1.99 | −0.40 | 2.15 | 0.46 |
| Percent Lean Mass (%) | −0.01 | 0.06 | −0.01 | 0.06 | 0.98 | −0.01 | 0.05 | −0.01 | 0.05 | 0.33 |
1
comparison between active and placebo for ET trial
2
comparison between active and placebo for EPT trial
BMI, Body Mass Index