Fig. 5.

Lysosomal pathology is predominant in infants. Fibers were stained for LAMP-2 (red)/LC3 (green). Clusters of autophagosomes are seen in some fibers [A (projection) and B]. Fibers from CLIN4 are shown in A, B, C, and F; fibers from NBS6 are shown in D and E. The dashed line marks a fiber that appears to be devoid of contractile elements. Bar: 10 microns. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)