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. Author manuscript; available in PMC: 2011 Oct 30.
Published in final edited form as: Adv Drug Deliv Rev. 2010 Aug 4;62(13):1257–1264. doi: 10.1016/j.addr.2010.07.008

Figure 2.

Figure 2

A schematic comparison of the domain structures of a typical nuclear receptor and PXR. AF-1, activation function 1; DBD, DNA binding domain; H, hinge region; LBD, ligand binding domain; AF-2, transactivation function 2.