Table 1.

Chemical structures and known activities of PXR inhibitors/antagonists

Compound	Structure	Other known activity	References
ET-743		Antineoplastic	Synold et al. [30]
Ketoconazole		Inhibiting CYP3A4 enzyme activity	Huang et al. [105]
Sulforaphane		Inhibiting histone deacetylases: inducing Phase II enzymes	Zhou et al. [107]
A-792611		Inhibiting HIV protease	Healan-Greenberg et al. [106]
Coumestrol		Agonist for estrogen receptors	Wang et al. [108]
Camptothecin		Inhibiting topoisomerase I	Chen et al. [109]