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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Inflamm Bowel Dis. 2010 Dec;16(12):2012–2021. doi: 10.1002/ibd.21320

Figure 3. Inflammation in Il10−/− mice with colitis that were supplemented with either fresh or boiled pineapple juice for up to 6 months.

Figure 3

Severe mucosal hyperplasia with architectural distortion and ulceration were commonly observed in the cecum (shown) and colon of mice fed boiled juice (A). Arrows point out the loss of mucosal epithelium and underlying inflammation and granulation tissue characteristic of an ulcer. Severe mucosal hyperplasia is demonstrated by the marked increase in mucosal thickness in (A) compared with mice fed fresh juice (B) who typically had only mild mucosal hyperplasia and inflammation. Panels were taken at the same magnification to emphasize the difference in mucosal hyperplasia between the 2 groups. Bar = 50 µm.