Table 1.

A summary of currently recognized functions, indications and contraindications of coenzyme Q₁₀

Functions[1]	Indications[2]	Contraindications[4]
Needed for energy conversion (ATP production)	Immune function Periodontal disease	No data have evaluated the safety or toxicity of CoQ10 during pregnancy, lactation or childhood. Therefore, its use is not recommended in these patient populations.
	Gastric ulcers
	Obesity
An essential antioxidant	Physical performance
	Muscular dystrophy	All natural products carry the potential for allergic reactions, however, to date, none have been reported with the use of CoQ10.[4]
Regenerates other antioxidants	Allergy
	Cardiovascular disease: Specific cardiac problems which may benefit include: Cardiomyopathy, congestive heart failure, angina, arrhythmias, prevention of adriamycin toxicity, protection during cardiac surgery, mitral valve prolapse, hypertension, male infertility, diabetes mellitus.
Stimulates cell growth and inhibits cell death
Decreased biosynthesis may cause deficiency