Table 2.
Comparison of various parameters of disease activity score
|
MTX + HCQ (Group 1) |
LEF (Group 2) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Sixth week | Twelfth week | P | Baseline | Sixth week | Twelfth week | P | |
| TJC | 19.03 ± 10.61 | 8.46 ± 8.70 | 15.03 ± 9.08 | 0.000* | 19.86 ± 9.22 | 7.96 ± 6.36 | 14.89 ± 7.80 | 0.000* |
| SJC | 8.56 ± 9.94 | 7.37 ± 9.06 | 7.90 ± 9.33 | 0.000* | 10.62 ± 9.90 | 8.41 ± 8.49 | 9.58 ± 9.32 | 0.000* |
| ESR | 40.70 ± 30.62 | 3.00 ± 38.49 | 28.50 ± 29.23 | 0.000* | 42.82 ± 23.90 | 14.37 ± 18.26 | 2924 ± 22.01 | 0.000* |
| PVAS | 82.50 ± 12.52 | 17.87 ± 16.87 | 54.10 ± 12.61 | 0.000* | 88.88 ± 6.08 | 23.45 ± 14.29 | 58.58 ± 8.19 | 0.000* |
Data shown is mean ± SD;
*
Statistically significant; Mtx = Methotrexate; HCQ = hydroxychloroquine; LEF = leflunomide; TJC = total joint count; SJC = swollen joint count; ESR = erythrocyte sedimentation rate; PVAS = pain as on Visual Analog Scale.