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. 2010 Nov 3;1:11. doi: 10.1186/2041-9139-1-11

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Copyright ©2010 Lang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Phylogeny of vertebrate shh. RaxML Maximum likelihood tree [64], (JTT Matrix), with shh protein sequences, rooted with human IHH. Numbers above nodes indicate bootstrap support (100 replicas) [GenBank accession numbers: SHH human: NM_000193.2, shh mouse: NM_009170.2, shh chick: NM_204821.1, shh zebrafish: NM_131063.1, twhh zebrafish: NM_131199.2, shh Fugu: AY690624.1, IHH human: XM_050846.3]. The deduced cds of Medaka (Oryzias latipes) and opossum (Monodelphis domestica) were extracted from genome data. The Latimeria menadoensis shh cds was deduced from DNA sequence alignments.