Table 1.
Laboratory characteristics of 30 nondiabetic patients with overt hypothyroidism before and after thyroid hormone replacement in study 2
| Before thyroid hormone replacement | After thyroid hormone replacement | P | |
|---|---|---|---|
| Age (years) | 47.3 ± 12.3 | — | |
| Sex (male/female) | 7/23 | — | |
| A1C (%) | 5.57 ± 0.26 | 5.37 ± 0.32 | <0.001 |
| GA (%) | 13.18 ± 1.35 | 12.52 ± 1.16 | 0.027 |
| GA-to-A1C ratio | 2.38 ± 0.29 | 2.35 ± 0.28 | 0.587 |
| Glucose (mmol/l) | 4.95 ± 0.41 | 5.24 ± 0.92 | 0.174 |
| 1,5-AG (μg/ml) | 20.03 ± 6.92 | 21.42 ± 7.45 | 0.086 |
| Hb (g/dl) | 14.05 ± 1.35 | 13.64 ± 1.23 | 0.004 |
| MCV (fL) | 88.29 ± 4.73 | 90.78 ± 4.75 | <0.001 |
| MCH (pg) | 29.48 ± 2.04 | 30.25 ± 1.95 | <0.001 |
| Reticulocyte (%) | 0.64 ± 0.18 | 1.09 ± 0.34 | <0.001 |
| Ferritin (ng/ml) | 74.34 ± 64.30 | 76.31 ± 57.58 | 0.689 |
| EPO (mIU/ml) | 12.93 ± 4.97 | 16.41 ± 6.44 | 0.022 |
| Albumin (g/l) | 43.5 ± 1.7 | 42.6 ± 1.6 | 0.009 |
| Total cholesterol (mmol/l) | 6.21 ± 1.23 | 4.37 ± 0.75 | <0.001 |
| Triglyceride (mmol/l) | 1.57 ± 1.01 | 1.62 ± 1.15 | 0.802 |
Data are means ± SD. Hb, hemoglobin.