Table 3.

Adjusted hazard ratios (95% CI) for diabetes medication prescription by follow-up smoking status, alcohol intake, and exercise in men and women of the Korean Cancer Prevention Study, 1992–2006

Follow-up characteristics	Men		Women
	≥1 prescription/365 days	≥3 prescriptions/365 days	≥1 prescription/365 days	≥3 prescriptions/365 days
Never smoker	1.0	1.0	1.0	1.0
Former smoker	1.17 (1.14–1.21)	1.28 (1.22–1.35)	1.06 (0.94–1.19)	1.09 (0.89–1.33)
Current smoker (cigarettes smoked daily)*
1–9	1.11 (1.07–1.15)	1.37 (1.29–1.45)	1.20 (1.09–1.31)	1.39 (1.20–1.62)
10–19	1.17 (1.14–1.20)	1.54 (1.48–1.61)	1.17 (1.04–1.32)	1.61 (1.35–1.93)
≥20	1.25 (1.21–1.29)	1.71 (1.63–1.80)	1.09 (0.85–1.39)	1.61 (1.12–2.30)
Alcohol intake (g/day)
0	1.0	1.0	1.0	1.0
1–24	0.96 (0.94–0.98)	0.96 (0.93–1.00)	0.98 (0.95–1.02)	0.96 (0.90–1.03)
25–49	0.99 (0.96–1.03)	1.01 (0.96–1.07)
50–99	1.02 (0.98–1.06)	1.09 (1.02–1.16)	2.21 (0.92–5.32)	5.61 (1.81–17.40)
≥100	0.95 (0.89–1.02)	1.00 (0.90–1.11)
Exercise	0.93 (0.91–0.95)	0.86 (0.83–0.89)	0.98 (0.94–1.01)	0.93 (0.87–0.99)

Hazard ratios were adjusted for age, age², alcohol drinking, BMI, and exercise. Data collection period for prescription medication was 2001 through 2005.

*P_trend < 0.0001 for any prescriptions in men and ≥3 prescriptions in women; P = 0.0062 for ≥1 prescription in women.