Table 2.
Mean age at amputation for the first major amputation and interval from diabetes registration to the first major amputation, adjusted for registration age, among men and women in the Y-ITDM, O-ITDM, and NITDM groups and nondiabetic individuals during the first (1997–2000) and last (2004–2007) 4 years of the observation period
| 1997–2000 |
2004–2007 |
Difference (P value)* | |||||
|---|---|---|---|---|---|---|---|
| No. amputees | Age at first major amputation (years) | Interval from diabetes registration to first major amputation (years) | No. amputees | Age at first major amputation (years) | Interval from diabetes registration to first major amputation (years) | ||
| Men | |||||||
| Y-ITDM | 122 | 54.1 (52.4–55.9) | 28.8 (27.6–30.1) | 115 | 54.4 (52.5–56.4) | 31.5 (30.1–32.8) | 2.6 (0.003) |
| O-ITDM | 119 | 70.4 (68.8–72.0) | 16.7 (15.2–18.1) | 67 | 68.7 (66.2–71.2) | 17.2 (15.2–19.1) | 0.5 (0.34) |
| NITDM | 703 | 72.0 (71.2–72.7) | 11.6 (11.1–12.0) | 751 | 71.9 (71.2–72.6) | 12.8 (12.4–13.3) | 1.3 (0.0001) |
| All diabetic | 944 | 69.5 (68.7–70.2) | 14.4 (14.0–14.8) | 933 | 69.5 (68.7–70.3) | 15.5 (15.0–15.9) | 1.1 (0.0002) |
| Nondiabetic | 844 | 70.3 (69.3–71.4) | 650 | 70.4 (69.1–71.7) | |||
| Women | |||||||
| Y-ITDM | 62 | 50.7 (48.1–53.2) | 28.8 (27.0–30.6) | 44 | 52.5 (49.3–55.7) | 33.4 (31.3–35.5) | 4.6 (0.0006) |
| O-ITDM | 100 | 75.0 (73.7–76.4) | 18.7 (17.4–20.0) | 67 | 77.2 (75.2–79.2) | 20.7 (19.1–22.3) | 2.0 (0.03) |
| NITDM | 888 | 79.1 (78.5–79.6) | 11.7 (11.3–12.1) | 625 | 79.7 (79.0–80.5) | 12.7 (12.2–13.2) | 1.0 (0.0004) |
| All diabetic | 1,050 | 77.0 (76.4–77.7) | 13.4 (13.0–13.8) | 736 | 77.9 (77.0–78.7) | 14.6 (14.2–15.1) | 1.3 (<0.0001) |
| Nondiabetic | 923 | 80.1 (79.3–80.9) | 840 | 80.7 (79.9–81.5) | |||
Data are means (95% CI) unless otherwise indicated.
*P value for the difference in interval between periods, adjusted for registration age (years).