Table 1.
Subject demographics and characteristics
| Healthy control | Diabetes with no neuropathy | Diabetes with neuropathy | |
|---|---|---|---|
| Age (years) | 49 ± 16.6 | 52.3 ± 15.8 | 63.7 ± 9.5*† |
| Sex (male/female) | 12/13 | 20/26 | 2326 |
| BMI (kg/m2) | 28.2 ± 6.2 | 32.4 ± 8.6 | 31.2 ± 6.3 |
| Height (m) | 1.70 ± 0.09 | 1.68 ± 0.08 | 1.69 ± 0.10 |
| Weight (kg) | 82 ± 19 | 92 ± 23 | 89 ± 19 |
| Systolic blood pressure (mmHg) | 118 ± 12 | 122 ± 13 | 130 ± 16*† |
| Diastolic blood pressure (mmHg) | 73 ± 9 | 73 ± 8 | 73 ± 8 |
| Heart rate (bpm) | 66 ± 9 | 70 ± 10 | 69 ± 11 |
| Diabetes type (1/2) | NA | 33/14 | 37/11 |
| Duration diabetes (years) | NA | 13.1 ± 10.3 | 16.4 ± 11.9 |
| A1C (%) | 5.5 ± 0.3 | 7.2 ± 1.0* | 7.0 ± 0.9* |
| Total cholesterol (mmol/l) | 195 ± 31 | 160 ± 38* | 168 ± 40* |
| Triglycerides (mmol/l) | 107 ± 50 | 124 ± 94 | 135 ± 84 |
| HDL cholesterol (mmol/l) | 61 ± 17 | 57 ± 19 | 57 ± 14 |
| LDL cholesterol (mmol/l) | 114 ± 31 | 78 ± 31* | 86 ± 34* |
| NSS | 0.2 ± 0.5 | 0.7 ± 1.0 | 4.5 ± 3.7*† |
| NDS | 0.2 ± 0.5 | 0.4 ± 0.8 | 6.3 ± 5.3*† |
Data are means ± SD. Characteristics of the study groups were compared by one-way ANOVA with Tamhane T2 post hoc tests. Diabetes type and duration were analyzed by χ2 and unpaired t tests accordingly. NA, not applicable.
*P < 0.01 vs. healthy control subjects;
†P < 0.01 vs. diabetes without neuropathy.