Table 3.

Performance of VPT testing on the great toe

	n*	Sensitivity	Specificity	PPV	NPV	% correct	κ
Definite clinical neuropathy
Total cohort	1,170	80 (76–84)	51 (47–54)	49	81	62	0.271
Aged 36–50 years	691	75 (69–81)	50 (46–55)	42	81	58	0.208
Aged 51–65 years	420	87 (82–92)	47 (41–54)	59	80	66	0.330
Abnormal nerve conduction
Total cohort	1,170	75 (72–78)	62 (58–67)	76	61	70	0.271
Aged 36–50 years	691	72 (68–77)	63 (57–68)	74	61	68	0.350
Aged 51–65 years	420	81 (76–85)	57 (48–65)	80	58	73	0.377
Confirmed clinical neuropathy
Total cohort	1,170	87 (84–91)	51 (47–54)	43	90	62	0.296
Aged 36–50 years	691	84 (78–89)	51 (46–55)	37	90	59	0.241
Aged 51–65 years	420	93 (89–97)	47 (41–53)	53	91	65	0.348

Data are % (95% CI) unless otherwise indicated.

*n = 7 subjects who are missing a great toe measurement.