FIGURE 1.

Altered O-GlcNAc cycling influences Drosophila body size. Third instar larvae or 4-day-old adults of dILP2GAL4/+;UAS-dOGTRNAi/+ (OGT-RNAi), dILP2GAL4/+;UAS-dOGARNAi/+ (OGA-RNAi), dILP2GAL4/+;UAS-myc-dOGT/+ (OGT-Myc), or control strains were collected. A, measurement of larval size. Data are expressed as the means ± S.E. (n = 20). *, p < 0.05 versus control. B, representative images of third instar larvae are shown. C, body weight measurement of adult flies. Data are expressed as the means ± S.E. (n = 25). *, p < 0.05 versus control. D, representative images of adult flies are shown.