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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Mol Oral Microbiol. 2010 Dec 1;25(6):418–425. doi: 10.1111/j.2041-1014.2010.00590.x

Fig. 2. Activity of peptide mimetics against biofilms of C. albicans.

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Biofilms were grown on saliva-coated denture material (A, B) or in saliva-coated wells of a chamber slide (C, D) for three days. Compounds were added to the growth medium for 24 hours, and metabolic activity was measured by XTT assay (n=3; results are mean +/- standard deviation) (A). In panel B, activity was measured by incubating biofilms with PMX30016, followed by plating the fungi to quantify viable organisms (results shown are representative of three independent experiments). Visualization of killing was carried out by Live/Dead staining followed by confocal fluorescent microscopy (C). D, Time course of exposure to 100μg/ml mPE with Live/Dead staining.