Figure 4: CD277 inhibits Th1 cytokine secretion by TCR-stimulated human T cells.

K32 cells expressing or not CD277 were loaded with anti-CD3 agonistic antibodies and cells were cocultured with human T cells as described above. Culture supernatants were collected after five days and cytokine secretion was analyzed by Multiplex analysis. Data are representative of two independent experiments with similar results. **P<0.05 (Mann-Whitney).