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. 2010 Dec;24(12):4648–4659. doi: 10.1096/fj.10-162230

Figure 3.

Figure 3.

ANGPTL4 stimulates osteoclast resorption. A, B) Effect of 24 h exposure to ANGPTL4 (1–100 ng/ml) on osteoclast (OC) viability (comparative number of VNR-positive, multinucleated cells; A) and relative resorption (area of resorption normalized to osteoclast number; B). C) 100 ng/ml ANGPTL4 has no effect on osteoclast number (VNR-positive multinucleated cells; i, ii) and stimulates resorption (iii, iv). D) Effect of 24 h exposure to ANGPTL4 (100 ng/ml) on resorptive capacity of primary human osteoclasts. **P < 0.01; ***P < 0.001.