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. 2010 Aug 8;1(4):265–277. doi: 10.18632/oncotarget.137

Figure 3: High-resolution mapping of homozygous deletions reveals ERRFI1 within the most frequent MDr on 1p36.23.

Figure 3:

(A) DK analysis of chromosome 1 in glioblastoma cell lines H423 and H502 reveals a single homozygous deletion at 1p36.23. (B) High resolution mapping depicts overlapping homozygous deletions from 6.0Mb to 10.0Mb coordinates on chromosome 1 (indicated by red bars). Copy number data include tumor samples from our independent analysis and the TCGA glioblastoma copy number data set. RefSeq gene positions are indicated. Validation by genomic Q-PCR copy number analysis (*) of H423, H502, and glioblastoma xenograft X298 confirms homozygous deletion. Q-PCR primer location depicted by black boxes (Supplemental Table S6).