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. 2010 Aug 8;1(4):265–277. doi: 10.18632/oncotarget.137

Figure 6: TACC3 is the predominant gene upregulated in 4p16.3 and correlates with Aurora kinase expression.

Figure 6:

SAGE of (A) TACC3 and FGFR3 and (B) Aurora kinases, AURKA, AURKB, and AURKC in normal brain (n = 2) and glioblastoma (n = 16) samples (data adapted from [5]). (C) Gene expression of TACC and Aurora kinase family members using the TCGA glioblastoma expression data set (n = 266) indicates correlation between TACC3 and AURKA (correlation coefficient = 0.76) and between TACC3 and AURKB (correlation coefficient = 0.70). Red indicates high gene expression level and green indicates low gene expression level.