Table 4.
Impact of clinical and demographic characteristics on the risk of breast cancer in Brazilian women
| Characteristic | Category | Cases | Controls | OR | 95%CI | P χ2 |
|---|---|---|---|---|---|---|
| Age* (years) | < 48 | 147 | 163 | 1 | ||
| ≥ 48 | 171 | 110 | 1.72 | (1.24-2.39) | 0.001 | |
| Missing data | 0 | 0 | ||||
| Menarche (Age) | < 12 | 120 | 93 | 1 | ||
| ≥ 12 | 120 | 74 | 1.25 | (0.84-1.86) | 0.258 | |
| Missing data | 78 | 106 | ||||
| Menopause (Age)** | ≤ 54 | 98 | 62 | 1 | ||
| ≥ 55 | 10 | 5 | 0.79 | (0.25-2.42) | 0.68 | |
| Missing data | 127 | 103 | ||||
| First Birth (Age) | ≤ 30 | 161 | 103 | 1 | ||
| ≥ 31 or nulliparous | 75 | 68 | 1.41 | (0.93-2.13) | 0.09 | |
| Missing data | 82 | 102 | ||||
| Fertile Time¥ | < 35 | 45 | 35 | 1 | ||
| ≥ 35 | 60 | 27 | 1.73 | (0.83-3.42) | 0.089 | |
| Missing data | 3 | 5 | ||||
| Use of contraceptives † | < 2 | 110 | 105 | 1 | ||
| ≥2 | 92 | 59 | 1.49 | (0.97-2.27) | 0.065 | |
| Missing data | 116 | 109 | ||||
| Use of HRTθ | no | 79 | 43 | 1 | ||
| yes | 25 | 20 | 0.68 | (0.32-1.44) | 0.276 | |
| Missing data | 4 | 4 | ||||
| Use of NSAIDs | no | 187 | 154 | 1 | ||
| yes | 31 | 13 | 1.96 | (0.99-3.88) | 0.053 | |
| Missing data | 100 | 106 | ||||
| BMI | Underweight: ≤ 18.4 | 9 | 1 | 4.13 | (0.50-33.6) | 0.28 |
| Normal: 18.5 - 24.9 | 98 | 45 | 1 | |||
| Overweight: ≥ 25.0 | 159 | 63 | 1.15 | (0.73-1.83) | 0.55 | |
| Missing Data | 52 | 164 | ||||
| Smoking Habit | no | 174 | 83 | 1 | ||
| yes | 98 | 38 | 1.23 | (0.77-1.94) | 0.42 | |
| Missing data | 46 | 152 | ||||
| Color | White | 131 | 120 | 0.619‡ | ||
| Intermediate | 125 | 96 | ||||
| Black | 62 | 57 | ||||
| Missing data | 0 | 0 |
* 48 years old is the median of cases + controls; ** Menopausal status: postmenopausal: cases n = 108, controls: n = 67; premenopausal: cases: n = 83, controls n = 103; ¥ Age of Menopause - Age of Menarche (only for women in menopause); † For at least 2 years; θHRT: Hormonal Reposition Therapy (only for women in menopause); NSAIDs: Non-Steroidal Anti-Inflammatory Drugs; BMI: Body Mass Index at diagnosis (patients) or at recruitment (controls), BMI = weight (Kg)/height2 (m2); OR: Odds Ratio; 95%CI: 95% Confidence Interval; P from Chi-square test (Pearson p-value); ‡ P from Fisher test.