Table 5.
Genotypic distribution of PTGS2 SNPs in cases and controls
| SNP | Population | N* | Genotypic Distribution N (Freq) | P χ2 | ||
|---|---|---|---|---|---|---|
| rs689465 | AA | AG | GG | |||
| Cases | 290 | 202 (0.69) | 83 (0.28) | 5 (0.03) | 0.927 | |
| Controls | 244 | 172 (0.70) | 67 (0.27) | 5 (0.03) | ||
| rs689466 | AA | AG | GG | |||
| Cases | 289 | 224 (0.77) | 62 (0.21) | 3 (0.02) | 0.968 | |
| Controls | 245 | 190 (0.77) | 51 (0.21) | 3 (0.02) | ||
| rs20417 | GG | GC | CC | |||
| Cases | 308 | 157 (0.51) | 127 (0.41) | 24 (0.08) | 0.731 | |
| Controls | 264 | 129 (0.49) | 117 (0.44) | 18 (0.07) | ||
| rs5275 | TT | TC | CC | |||
| Cases | 294 | 125 (0.42) | 149 (0.51) | 20 (0.07) | 0.046 | |
| Controls | 244 | 120 (0.49) | 99 (0.41) | 25 (0.10) | ||
N: Number of examined samples (with available PCR amplification); * Differences in sample sizes for cases and controls are due to available data in each category. Freq: Frequency; P χ2: P from Chi-square test (Pearson p-value).