Table 4.
OS and EFS in patients35 years and younger with local breast cancer
| No. of patients | 3-Year OS(%) | P | 3-Year EFS(%) | P | |
|---|---|---|---|---|---|
| Stage I-III | 356 | 83.2 | - | 62.5 | - |
| Tumor size | |||||
| T1 | 48 | 89.3 | 0.76 | 75.9 | 0.32 |
| T2 | 161 | 85.5 | 65 | ||
| T3 | 71 | 79.5 | 56 | ||
| T4 | 76 | 77.5 | 55.2 | ||
| SBR grading | |||||
| SBR I | 14 | 100 | 0.20 | 67.5 | 0.45 |
| SBR II | 176 | 84.9 | 63.2 | ||
| SBR III | 137 | 78 | 58.8 | ||
| ER | |||||
| ER positive | 179 | 94.4 | 0.001 | 75.8 | 0.001 |
| ER negative | 149 | 70.2 | 50.6 | ||
| N stage | |||||
| N0 | 107 | 79.4 | 0.32 | 59.8 | 0.20 |
| N+ | 249 | 84.8 | 63.6 | ||
| Surgery type | |||||
| Radical mastectomy | 265 | 82.3 | 0.17 | 61.9 | 0.059 |
| Conserving surgery |
80 | 87.7 | 70.4 | ||
| Adjuvant radiotherapy | |||||
| Yes | 290 | 85.2 | 0.002 | 65.7 | 0.001 |
| No | 66 | 70.2 | 48.6 | ||
| Adjuvant chemotherapy | |||||
| No | 45 | 65.4 | 0.04 | 44.7 | 0.001 |
| Yes | 311 | 85 | 64.9 | ||
| Hormonotherapy | |||||
| Yes | 232 | 85.9 | 0.001 | 69.5 | 0.001 |
| No | 124 | 76.6 | 48 | ||
| Stage | |||||
| I | 30 | 100 | 0.001 | 93 | 0.001 |
| II | 140 | 89.4 | 76.3 | ||
| III | 186 | 74.7 | 46.8 | ||
ER. estrogen receptors; N. lymph node; CI. confidence interval; OS. overall survival; EFS. event free survival.