Table 5.

Cox Proportional Hazards Model of Overall Survival for patients with local disease:

	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
Family history
No	1.00			1.00
Yes	1.10	0.47 - 2.58	0.83	1.12	0.44-2.88	0.81
SBR grading
SBR I	1.00			1.00
SBR II	2.01	0.27 - 14.6	0.49	1.26	0.15-10.9	0.83
SBR III	2.55	0.35 - 18.69	0.36	1.03	0.12-8.76	0.97
Tumor size
T1	1.00			1.00
T2	1.54	0.65 - 3.66	0.33	2.25	0.50-10.19	0.30
T3	1.55	0.59 - 4.1	0.38	2.50	0.47-13.42	0.29
T4	1.64	0.64 - 4.23	0. 31	2.34	0.44-12.44	0.32
N statut
N-	1.00			1.00
N+	0.78	0.47 - 1.28	0.32	0.62	0.29-1.30	0.20
Stage
I	1.00			1.00
II	2.10	0.53 - 8.37	0.29	1.43	0.24-8.57	0.69
III	4.24	1.1 - 16.28	0.03	3.56	0.65-19.57	0.14
ER
ER positive	1.00			1.00
ER negative	2.25	1.37 - 3.72	0.001	2.54	1.32- 4.90	0.005
Adjuvant chemotherapy
No	1.00			1.00
Yes	0.49	0.24 - 0.99	0.04	0.74	0.18-3.05	0.68
Adjuvant hormonotherapy
No	1.00			1.00
Yes	0.45	0.28 - 0.73	0.001	0.89	0.45-1.77	0.74
Surgery type
Radical mastectomy	1.00			1.00
Conserving surgery	0.64	0. 34 - 1.23	0.17	0.50	0.19-1.18	0.11
Adjuvant radiotherapy
No	1.00			1.00
Yes	0.42	0.24-0.74	0.003	0.74	0.25-2.23	0.60

1. Reference; ER. estrogen receptors; N. lymph node; CI. confidence interval; OS. overall survival; EFS. Events free survival.