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. Author manuscript; available in PMC: 2010 Nov 29.
Published in final edited form as: Neuropsychopharmacology. 2007 Mar 14;32(12):2601–2610. doi: 10.1038/sj.npp.1301382

Fig 3. Experiment 2: A two-week administration of SR 48692 does not alter cocaine–induced locomotor activity in saline pre-exposed rats.

Fig 3

The experimental protocol was similar to that performed in experiment 1. However, in this experiment, rats (n= 24) received saline injections (i.p.) on days 1, 3, 5, 7, 14 and 21, and a single cocaine challenge (15 mg/kg, i.p.) was performed on day 28. Daily administration of SR 48692 (1 mg/kg, i.p., n= 12) or vehicle (n=12) was performed from day 15 to day 28. Data represent mean ± SEM of crossovers (A) or rearings (B) summed over 5 minutes.