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. Author manuscript; available in PMC: 2010 Nov 26.
Published in final edited form as: Curr Opin Plant Biol. 2007 May 3;10(3):323–330. doi: 10.1016/j.pbi.2007.04.015

Figure 3.

Figure 3

Changes in glucose concentration in HepG2 cells stably expressing FLIPglu600 μ. (a) External perfused glucose concentration. (b) Measured yellow fluorescent protein (YFP)/cyan fluorescent protein (CFP) emission ratios and simulation curve based on a kinetic model. (c) Cytosolic glucose concentration from simulation. (d) Underlying compartment model for analysis of glucose homeostasis in HepG2 cells (modified from Fehr et al. [31••]). Glucose is transported reversibly across the plasma and ER membranes and is phosphorylated irreversibly in the cytosol.