Table 1.
Percent of body weight change during methylene blue (MB) administration. The table shows the average body weight of each group of mice per each week of treatment. Weights were not taken on week 9 or 14.
| Mice | Treatment | % Weight change during the 16 weeks of treatment | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 10 | 11 | 12 | 13 | 15 | 16 | ||
| 3xTg‐AD (n = 17) | MB | 0 | −0.02 ± 2.22% | −0.82 ± 2.11% | 1.44 ± 2.26% | −1.88 ± 1.81% | 2.30 ± 1.42% | 1.84 ± 1.58% | 1.56 ± 1.35% | 1.66 ± 1.10% | 2.94 ± 0.99% | 3.36 ± 1.11% | 4.74 ± 1.41% | 4.00 ± 1.18% | 5.08 ± 1.44% |
| 3xTg‐AD (n = 14) | CTL | 0 | −6.05 ± 3.50% | −0.48 ± 3.89% | −2.53 ± 2.84% | −2.48 ± 4.02% | 0.60 ± 4.46% | 1.13 ± 4.60% | 0.87 ± 4.79% | 0.29 ± 4.79% | 1.06 ± 4.03% | 0.84 ± 4.55% | 0.99 ± 4.62% | −1.83 ± 3.68% | 0.53 ± 3.43% |
| NonTg (n = 13) | MB | 0 | 0.48 ± 3.11% | 0.20 ± 1.84% | 0.58 ± 1.84% | 1.51 ± 1.63% | −0.35 ± 1.77% | 0.73 ± 1.76% | −0.68 ± 1.92% | 0.28 ± 1.34% | 0.48 ± 1.15% | −1.34 ± 1.3% | 0.30 ± 1.66% | 1.11 ± 1.60% | 1.36 ± 1.64% |
| NonTg (n = 10) | CTL | 0 | 3.15 ± 1.88% | 2.65 ± 1.64% | −0.37 ± 7.32% | 3.35 ± 2.16% | 4.72 ± 2.47% | 6.90 ± 2.80% | 5.76 ± 2.70% | 6.76 ± 2.53% | 6.53 ± 2.30% | 5.66 ± 2.65% | 6.50 ± 2.80% | 6.56 ± 2.79% | 7.17 ± 2.79% |