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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neurobiol Aging. 2010 Aug 19;33(6):1085–1095. doi: 10.1016/j.neurobiolaging.2010.07.002

Figure 1.

Figure 1

Characterization of the sIAHP in representative layer 3 pyramidal cells. A) Response to increasing amplitude depolarizing 200 ms voltage prepulses. B) Response of a representative layer 3 pyramidal cell to increasing duration depolarizing prepulses. C) Voltage-independence of the sIAHP tail current demonstrated by a consistent step to −5 mV for 100 ms, followed by a voltage step to −95 to −35 mV. D) Near complete block of the sIAHP by bath application of isoproterenol (10 μM). Scale bars: A= 35 mV, 100 pA/100 ms; B= 30 mV, 20 pA/1 s; C= 25 mV, 200 pA/500 ms; D= 30 mV, 100 pA/200 ms.