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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neurobiol Aging. 2010 Aug 19;33(6):1085–1095. doi: 10.1016/j.neurobiolaging.2010.07.002

Figure 3.

Figure 3

The amplitude of the sIAHP is unaltered with age in layer 5 pyramidal cells. A) sIAHPs evoked by increasing depolarizing voltage steps in representative cells from young (left), aged-unimpaired (middle) and aged-impaired monkeys (right). B) No significant correlation between sIAHP amplitude and age is seen in all monkeys (left) or in the aged cohort only (right). C) Line graph plotting mean sIAHP amplitude as a function of voltage step for cells from young, aged-unimpaired and aged-impaired monkeys. Inset: superimposed traces of sIAHPs evoked by +20 mV prepulses in cells from young, aged-unimpaired and aged-impaired monkeys. D) Mean sIAHP amplitude vs. firing rate evoked by a +180 pA 2 s current step. Linear regression line demonstrates no significant relationship between sIAHP amplitude and firing rate. Scale bars: 50 pA/100 ms.