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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Neurobiol Aging. 2010 Aug 19;33(6):1085–1095. doi: 10.1016/j.neurobiolaging.2010.07.002

Figure 4.

Figure 4

Relationship of sIAHP amplitude to overall CII z-score. A) Top, all subjects: mean sIAHP amplitude in layer 3 pyramidal cells from a given monkey vs. the CII z-score for that monkey. Linear regression line demonstrates a significant positive correlation. Bottom, aged subjects only: mean sIAHP amplitude for a given monkey vs. the CII z-score for that monkey. Linear regression line demonstrates a significant positive correlation. B) Top, all subjects: mean sIAHP amplitude in layer 5 pyramidal cells for a given monkey vs. the CII z-score for that monkey. Linear regression line demonstrates no correlation. Bottom, aged subjects only: mean sIAHP amplitude for a given monkey vs. the CII z-score for that monkey in the aged cohort of monkeys only. Linear regression line demonstrates no correlation. C) Bar graph giving mean sIAHP amplitudes in layer 3 cells from young (n = 8), aged-unimpaired (n = 4) and aged-impaired monkeys (n = 8). D) Bar graph giving mean sIAHP amplitudes in layer 5 cells from young (n = 8), aged-unimpaired (n = 4) and aged-impaired monkeys (n = 5). Dashed lines in A and B correspond to a z-score of 2.5, subjects with z-scores above this line are considered significantly impaired. * p < 0.001.