Table 3.

Electrophysiological Properties of dlPFC Pyramidal Cells

	YOUNG		AGED
	Mean	SEM	Mean	SEM	p <
LAYER 3
Vr (mV)	−67.9	0.58	−67.1	0.49	ns
Rn (MΩ)	114.5	7.29	118.0	4.36	ns
Firing Rate (Hz)
30 pA Step	0.99	0.43	1.42	0.32	ns
180 pA Step	10.3	0.95	13.6	0.62	0.004
280 pA Step	13.5	0.87	15.9	0.69	0.03
sIAHP Amp (pA)
−10 mV Step	45.1	5.07	57.3	5.27	ns
0 mV Step	78.3	7.64	95.7	7.84	ns
10 mV Step	84.7	9.09	112.4	8.90	0.05
20 mV Step	108.2	11.1	139.1	9.97	0.05
LAYER 5
Vr (mV)	−66.3	0.83	−67.1	0.76	ns
Rn (MΩ)	150.0	7.21	148.8	7.49	ns
Firing Rate (Hz)
30 pA Step	1.7	0.53	3.0	0.64	ns
180 pA Step	13.4	0.78	16.0	1.14	ns
280 pA Step	16.9	0.66	18.9	1.14	ns
sIAHP Amp (pA)
−10 mV Step	63.2	8.68	68.1	11.1	ns
0 mV Step	89.4	11.9	98.5	15.4	ns
10 mV Step	116.4	14.8	126.7	18.7	ns
20 mV Step	139.6	16.3	152.7	21.5	ns