Table 10.
Group | CASP-2 | CASP-3 | CASP-8 | CASP-9 |
Stress (-) | ||||
Veh | 18 ± 3 | 20 ± 2 | 21 ± 5 | 22 ± 4 |
Cer | 27 ± 3 | 29 ± 4 | 32 ± 5 | 29 ± 3 |
Anti-TNF-α + Cer | 26 ± 2 | 24 ± 3 | 24 ± 4 | 22 ± 3 |
Stress (+) | ||||
Veh | 97 ± 11 | 103 ± 9 | 99 ± 8 | 104 ± 12 |
Cer | 853 ± 81a | 912 ± 101a | 824 ± 77a | 917 ± 85a |
Anti-TNF-α + Cer | 597 ± 48c | 592 ± 55c | 560 ± 45c | 568 ± 47c |
Lung caspases are expressed as pmol/min per milligram protein.
P < 0.05 vs control-vehicle Stress (-) group;
P < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α; CASP: Caspase.