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The Reported Amino Acid Proteolytic Cleavage Sites within Laminin-332
| Chain | A.A. Position | Protease |
|---|---|---|
| α3 | Lys(191)-Asp(192) | BMP-1 |
| Gln(1337)-Asp(1338) | serine protease | |
| β3 | Ala(515)-Ile(516) | MMP-7 |
| γ2 | Gly(434)-Asp(435) | BMP-1, MT1-MMP |
| Gly(559)-Asp(560) | MT1-MMP | |
| Gly(579)-Ser(580) | MT1-MMP | |
| γ2rat | Gly(413)-Asp(414) | MT1-MMP |
| Ala(586)-Leu(587) | MT1-MMP, MMP-2, 3, 12,13, 20 | |
| Leu(587)-Thr(588) | MMP-8 | |
| Gly(413)-Asp(414) | MMP-14 |
