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. 2010 Sep 14;59(12):3008–3016. doi: 10.2337/db10-0483

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© 2010 by the American Diabetes Association.

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FIG. 2. — A: White adipose tissue (WAT) explants secretory proteins are secreted in greater amounts from VAT. B: Preadipocyte secreted proteins are secreted at greater amounts from visceral-derived preadipocytes. C: Endothelial cell secretory proteins are secreted at greater amounts from visceral-derived endothelial cells. WAT explants, preadipocytes, and microvascular endothelial cells from visceral and subcutaneous WAT depots were cultured in media containing two different isotopes of arginine and lysine. LAC–CILAIR mass spectrometry was performed, and isotopic ratios were calculated. The histogram shows distribution of visceral-to-subcutaneous ratios for proteins detected. Note the use of the natural log scale.