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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Exp Hematol. 2010 Aug 26;38(12):1131–1142.e1. doi: 10.1016/j.exphem.2010.08.003

Figure 3.

Figure 3

Mobilizations of Oct-4 positive pluripotent VSELs in ischemic heart disease patients and controls. Panel A. Representative Image Stream pictures of circulating Oct-4 positive VSELs lacking the expression of hematopoietic lineages (Lin) and CD45 markers (Green) and positive for Oct-4 (yellow) and CD34 or CD133 (magenta). Nuclei are stained with 7-AAD (red). The combined image in the far right demonstrates the co-localization of Oct-4 in the nucleus. Panel B. Bar graphs showing the absolute numbers of circulating Lin-/CD45−/CD34+/Oct-4+ cells in the peripheral blood of ischemic heart disease patients and controls; showing a peak mobilization early in STEMI patients. Panel C. Bar graphs showing the absolute numbers of circulating Lin-/CD45−/SSEA-4+ cells in the peripheral blood of ischemic heart disease patients and controls; showing a peak mobilization early in STEMI patients. (* P < 0.05 as compared to controls). NSTEMI, non-ST-elevation myocardial infarction; PB, peripheral blood; STEMI, ST-elevation myocardial infarction.