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The effect of MG132 on the Tro-induced alteration in mitochondrial function. (A) The amounts of mitochondrial mass with or without 5 µM MG132 pretreatment in the presence of increasing amounts of Tro were measured. (B–C) mRNA expression levels of (B) Tfam and (C) ATP5b were measured. (A–C) Drug treatments for 24 h were performed in HepG2 cells cultured in 2.5% FBS. (B–C) The relative level under dimethyl sulphoxide treatment was set as 1. **P < 0.01, ***P < 0.001.
