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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Transpl Int. 2010 Nov;23(11):1179–1189. doi: 10.1111/j.1432-2277.2010.01120.x

Figure 2. Donor skin graft survival is significantly prolonged in the absence of NKT cells.

Figure 2

Groups of mice received 1 Gy TBI with costimulation blockade and were grafted with donor and third party skin; donor skin graft survival for WT→WT (■ solid line; n= 8); donor skin graft survival for KO→KO (● slashed line; n= 6). Absence of NKT cells was associated with significantly prolonged survival of donor skin (p= 0.004 by log-rank test). Percent graft survival is shown for third-party (△ dotted line; pooled data from both groups; n= 14) and donor skin as estimated by the Kaplan-Meier product limit method.