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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Transpl Int. 2010 Nov;23(11):1179–1189. doi: 10.1111/j.1432-2277.2010.01120.x

Figure 5. Abrogation of BM engraftment through stimulation of NKT cells is mediated by NK cells.

Figure 5

Groups of mice were treated with anti-NK1.1 (depleting NK and NKT cells) plus alpha-gal (A), or in vivo TCD plus anti-asiolo GM1 (depleting NK cells) (B) (3 Gy TBI with costimulation blockade). One group of NKT KO mice received NKT KO BMC and was treated with CB plus anti-NK1.1 (D) (1 Gy TBI). In panel (C), chimerism is shown for mice receiving the same protocol as mice in (D), except that they were not treated with anti-NK1.1. Panel (C) is identical with figure 1 H and is shown here again for reasons of better clarity.