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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Mol Microbiol. 2009 Dec 4;75(2):452–461. doi: 10.1111/j.1365-2958.2009.06999.x

Figure 4. Model for the association of helicase and helicase loader with oriC in vivo.

Figure 4

The inner surface of the cell membrane is depicted as a gray bar across the top of each panel. DNA is depicted as a double helix with oriC bound to DnaA. Shapes with letters represent the proteins: A=DnaA (initiator), B=DnaB, D=DnaD, I=DnaI (loader ATPase), C=DnaC (helicase). Established protein-protein and protein-DNA interactions (see text) are also shown, except for self-interactions.