Effects of flavonoids against MeHg-induced mitochondrial GSH depletion. Mitochondrial enriched fractions were isolated from mouse brains and incubated with MeHg (100 μM) and (A) myricetin, (B) myricitrin and (C) rutin (0.03, 0.1 and 0.3 mM). After incubations (30 min at 25 °C), mitochondrial GSH levels were determined as non-protein thiols (NPSH). Data are expressed as nmol/mg protein (mean ± SE; n = 6).
*** (p<0.001) when compared to the control group by one-way ANOVA, followed by Duncan's multiple range test.