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. Author manuscript; available in PMC: 2010 Nov 29.
Published in final edited form as: J Neural Transm (Vienna). 2008 Oct 31;115(12):1673–1679. doi: 10.1007/s00702-008-0131-7

Table 1.

The effects of chronic antidepressant treatment on brain regional 2-arachidonylglycerol content.

Control 2-AG (nmol/g tissue)
Tranylcypromine Fluoxetine
Prefrontal Cortex 4.58 +/− 0.43 5.69 +/− 0.23* 5.16 +/− 0.36
Hippocampus 8.27 +/− 0.22 7.76 +/− 0.55 9.13 +/− 0.75
Hypothalamus 7.81 +/− 0.52 7.15 +/− 0.73 8.06 +/− 0.89

Twenty one days of tranylcypromine (10 mg/kg) or fluoxetine (5 mg/kg) treatment did not result in any changes in the content of 2-arachidonylglycerol (2-AG), except a significant increase in 2-AG content in the prefrontal cortex following tranylcypromine treatment. Data are presented as mean values +/− SEM.

*

Significantly different from control (p < .05).