Table 1.
Body weight and plasma parameters of hyperthyroid mice. Chow-fed Balb/c mice were treated with T3 or PBS for 14 days. (n=6-12 per group, unless otherwise stated). fT3, free triiodothyronine; fT4, free tetraiodothyronine.
| Control | T3 | P-value | |
|---|---|---|---|
| Body weight (g) | 19.6 ± 1.5 | 20.7 ± 2.3 | 0.34 |
| Plasma fT3 (pmol/l) | 1.8 ± 0.0 | 8.8 ± 0.3 | < 0.001 |
| Plasma fT4 (pmol/l) | 17.4 ± 4.4 | non detectable | < 0.001 |
| Plasma cholesterol (mg/dl) | 89.8 ± 19.2 | 54.2 ± 5.3 | < 0.001 |
| Plasma triglycerides (mg/dl) | 112.0 ± 23.7 | 123.3 ± 50.3 | 0.63 |
| Biliary cholesterol (μg/μl) | 2.8 | 5.7 | (Pooled bile) |