Skip to main content
. 2010 Dec;43(6):635–640. doi: 10.1165/rcmb.2009-0297OC

Figure 1.

Figure 1.

(A) Ciliary beat frequency (CBF) in tracheal epithelial cells of mice exposed to cigarette smoke. No change in baseline CBF was evident in mice exposed to cigarette smoke for 1.5 months and 3 months. Smoke exposure for 6 mo caused a small but significant (#P < 0.05) decrease in baseline CBF of media-only cells. From 9 months onward, baseline CBF slowed significantly (*P < 0.01). Vertical axis represents the mean (±SEM) of CBF (n = 10). (B) Ciliary beat frequency (CBF) in tracheal epithelial cells stimulated with a β-agonist, isoproterenol (Iso; 10 μM), from mice exposed to cigarette smoke. Isoproterenol was able to stimulate an increase in CBF in mice exposed to smoke for 1.5 to 3 months. However, isoproterenol failed to stimulate an increase in CBF of mice exposed to smoke for 6 months or longer. Vertical axis represents the mean (±SEM) ΔCBF (n = 10).