Figure 9.

Effect of endogenous tPA and uPA on tracheal reactivity. Contraction of tracheal rings isolated from tPA^−/−, uPA^−/−, or uPAR^−/− mice was induced by Ach, as described in Figure 1, in the absence or presence of 20 nM tPA or 20 nM uPA. The mean (±SD) of three experiments is shown.